Irritable Bowel Syndrome

(Functional Colitis; IBS; Intestinal Neurosis; Irritable Colon; Laxative Colitis; Mucous Colitis; Spastic Colon)

Definition

Definition

Irritable bowel syndrome (IBS) is a chronic disorder of the intestines. IBS does not cause inflammation and does not lead to a more serious condition.

Causes

Causes

The cause is unknown. With IBS, the muscles in the colon do not work normally and may spasm. If you have IBS, your colon may be more sensitive, reacting strongly to food and medication. Food allergies and certain bacteria may add to the symptoms. IBS may also occur after having the stomach flu (called gastroenteritis).

Risk Factors

Risk Factors

IBS is more common in women. It typically begins in young adulthood.

These factors may increase your chance of developing IBS:

Symptoms

Symptoms

Symptoms usually come and go, and range from mild to severe. They include:

  • Abdominal cramps
  • Gas and bloating
  • Pain that resolves with a bowel movement
  • Loose stools
  • Diarrhea
  • Constipation
  • Alternating diarrhea and constipation
  • Urge to move bowels again immediately following a bowel movement
  • Mucus in the stool

These factors may worsen your symptoms:

  • Stress
  • Menstrual periods
  • Large meals or fatty foods
  • Excess gas

Diagnosis

Diagnosis

You will be asked about your symptoms and medical history. A physical exam will be done. In many cases, a diagnosis can be made based on this. Since there is no diagnostic test for IBS, doctors have created criteria for making a diagnosis.

Your bodily fluids and waste products may be tested. This can be done with:

  • Stool tests
  • Blood tests

Your body structures may need to be viewed. This can be done with:

Colonoscopy

Copyright © Nucleus Medical Media, Inc.

Treatment

Treatment

There is no cure for IBS. Treatment focuses on controlling symptoms.

Diet

The following changes to your diet may help control symptoms:

  • Keep a food diary of what you eat and how your body responds. Share this with your doctor. You may have a food allergy.
  • Make gradual changes to your diet. Record the results.
  • Avoid foods that have caused problems in the past. A dietitian can help you substitute foods.
  • Avoid foods and drinks that may cause symptoms:

    • High fat foods, spicy foods
    • Dairy products
    • Onions, cabbage, and other gas-producing food
    • Large amounts of alcohol or caffeine
  • Eat foods that may reduce the chance of spasm, such as:

  • Eat smaller meals more often or smaller portions.
  • Eat slowly and try not to swallow air.
  • Drink plenty of water. This will help to reduce constipation.

Exercise

Participating in a regular exercise program can help improve bowel function and other IBS symptoms. If you would like to start exercising, check with your doctor to make sure you are healthy enough.

Stress Management

Talk to your doctor about ways to reduce stress, such as:

Education

Learn as much as you can about IBS and ways that you can reduce your symptoms. You may also find it helpful to join a support group.

Medication

Depending on your symptoms, your doctor may recommend:

  • Antispasmodic agent
  • Antibiotics
  • High-fiber bulking agent
  • Antiflatulent
  • Antidiarrheal agent
  • Low-dose antidepressant
  • Pain reliever
  • Serotonin receptor agonists and antagonists (also called 5-HT3 antagonists)—may be helpful for treating diarrhea, as well as treating other IBS symptoms, like abdominal pain in women
  • Probiotics
  • Peppermint oil

In some cases, your doctor may recommend that you take a combination of medications.

Prevention

Prevention

There are no guidelines for preventing IBS because the cause is unknown.

RESOURCES:

American College of Gastroenterology http://gi.org

American Gastroenterological Association http://www.gastro.org

CANADIAN RESOURCES

Canadian Digestive Health Foundation http://www.cdhf.ca

Health Canada http://www.hc-sc.gc.ca

References:

Acidophilus and other probiotics. EBSCO Natural and Alternative Treatments website. Available at:
http://www.ebscohost.com/healthLibrary/
Updated November 10, 2014. Accessed December 19, 2014.

Drossman DA. Treatment for bacterial overgrowth in the irritable bowel syndrome. Ann Intern Med. 2006;145:626-628.

Halvorson HA, Schlett CD, et al. Postinfectious irritable bowel syndrome—a meta-analysis. Am J Gastroenterol. 2006;101:1894-1899.

Irritable bowel syndrome. American Society of Colon and Rectal Surgeons website. Available at:
http://www.fascrs.org/patients/conditions/irritable_bowel_syndrome/
Update October 2012. Accessed December 19, 2014.

Irritable bowel syndrome. EBSCO DynaMed website. Available at:
http://www.ebscohost.com/dynamed
Updated October 21, 2014. Accessed December 19, 2014.

Irritable bowel syndrome. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at:
http://www.niddk.nih.gov/health-information/health-topics/digestive-diseases/ibs/Pages/facts.aspx
Updated June 25, 2014. Accessed December 19, 2014.

Murch S. Allergy and intestinal dysmotility—evidence of genuine causal linkage? Curr Opin Gastroenterol. 2006;22:664-668.

Rubin G, De Wit N, et al. The diagnosis of IBS in primary care: consensus development using nominal group technique. Family Practitioner. 2006;23:687-692.

Talley NJ, Boyce PM, et al. Is the association between irritable bowel syndrome and abuse explained by neuroticism? A population based study. Gut.1998;42: 47-53.

Yan F, Polk DB. Probiotics as functional food in the treatment of diarrhea. Current Opinion in Clinical Nutrition and Metabolic Care. 2006;9:717-721.

9/26/2006 DynaMed’s Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Mueller-Lissner S, Tytgat GN, et al. Placebo-and paracetamol-controlled study on the efficacy and tolerability of hyoscine butylbromide in the treatment of patients with recurrent crampy abdominal pain. Alimentary Pharmacology and Therapeutics. 2006;23:1741-1748.

4/10/2007 DynaMed’s Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
US Food and Drug Administration. FDA announces discontinued marketing of GI drug, Zelnorm, for safety reasons [press release]. March 30, 2007. US Food and Drug Administration website. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2007/ucm108879.htm. Accessed December 19, 2014.

1/6/2009 DynaMed’s Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Ford AC, Talley NJ, et al. Effect of fibre, antispasmodics, and peppermint oil in the treatment of irritable bowel syndrome: systematic review and meta-analysis. BMJ . 2008;337:a2313.

10/9/2009 DynaMed Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Lee S, Wu J, et al. Irritable bowel syndrome is strongly associated with generalized anxiety disorder: a community study. Aliment Pharmacol Ther. 2009;30(6):643.

11/4/2009 DynaMed Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Ford AC, Brandt LJ, et al. Efficacy of 5-HT3 antagonists and 5-HT4 agonists in irritable bowel syndrome: systematic review and meta-analysis. Am J Gastroenterol. 2009;104(7):1831-1843.

1/11/2010 DynaMed’s Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Wittmann T, Paradowski L, et al. Clinical trial: efficacy of alverine citrate/simeticone combination on abdominal pain/discomfort in irritable bowel syndrome: results of a randomized, double-blind, placebo-controlled study. Aliment Pharmacol Ther. 2009 Dec 10. [Epub ahead of print]

7/16/2010 DynaMed’s Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Dorn SD. Systematic review: self-management support interventions for irritable bowel syndrome. Aliment Pharmacol Ther. 2010 May 22. [Epub ahead of print]

1/14/2011 DynaMed’s Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Pimentel M, Lembo A, et al. Rifaximin therapy for patients with irritable bowel syndrome without constipation. N Engl J Med. 2011;364(1):22-32.

4/22/2011 DynaMed’s Systematic Literature Surveillance
http://www.ebscohost.com/dynamed:
Johannesson E, Simrén M, et al. Physical activity improves symptoms in irritable bowel syndrome: a randomized controlled trial. Am J Gastroenterol. 2011 Jan 4. [Epub ahead of print]

Last reviewed December 2014 by Daus Mahnke, MD
Last Updated: 12/20/2014

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.